Real Madrid will try to get their first victory ever at Anfield Road as they meet Liverpool in the third date of the Champions League.
Los Blancos will look to make it nine points in three games, and consolidate their lead in Group B. Liverpool need to regain confidence after their defeat in Basel and they will be specially motivated for this game.
Carlo Ancelotti has Sami Khedira back, and the German could play his first match of the season in the Champions League. However, it seems highly unlikely that he will make it in the starting eleven.
The Italian manager will miss Gareth Bale, who will sit out for the next two weeks following a muscle injury, and Sergio Ramos, who will rest ahead of El Clasico against Barcelona.
Fabio Coentrao and Jese Rodriguez will also sit out, still recovering from their injuries. Meanwhile, Karim Benzema and Raphael Varane return after recovering from a bout of flu. The defender will start at centre-back alongside Pepe, while the striker will accompany Cristiano Ronaldo up front.
Brendan Rodgers will only miss Daniel Sturridge, who has suffered a relapse from a previous calf injury.
Liverpool: Mignolet; Manquillo, Skrtel, Lovren, Jose Enrique; Gerrard, Henderson, Lallana; Sturridge, Lambert, Balotelli.
Real Madrid: Casillas; Carvajal, Pepe, Varane, Marcelo; James, Modric, Kroos, Isco; Ronaldo, Benzema.