The main doubt for Zinedine Zidane ahead of the match against Betis was whether to include James Rodriguez or Jese Rodriguez in the line-up. The Frenchman has finally decided to include the Colombian in the starting XI.
James will replace injured Gareth Bale, featuring in the right side of the attack. Isco will play on the other side, with Luka Modric and Toni Kroos in the centre. Cristiano Ronaldo and Karim Benzema will be Los Blancos strikers.
In the defence, Zizou has finally decided not to risk Sergio Ramos and has left him out of the squad. Raphael Varane and Pepe will be the centre-back pair, with Marcelo as the left-back. Danilo will replace Daniel Carvajal in the right-back.
There are no big surprises in Betis starting eleven. The main doubt was whether Juan Merino would line-up Real Madrid target Dani Ceballos or youngster Fabian in the playmaker position. The Spanish manager has chosen Fabian.
These are the confirmed starting line-ups:
Real Madrid: Navas; Danilo, Pepe, Varane, Marcelo; James, Modric, Kroos, Isco; Benzema, Ronaldo.
Betis: Adan; Molinero, Pezzella, Bruno, Vargas; Ndiaye, Petros; Kadir, Fabian, Cejudo; Castro.